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PDF Open Access Analog peptides of type II collagen can suppress ...

HLA-DR4 (DRB1*0401) transgenic mice Yoshihiko Sakurai 1,2 , David D Brand 3 , Bo Tang 1 , Edward F Rosloniec 3 , John M Stuart , Andrew H Kang 1,3 and Linda K Myers 4

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Analog peptides of type II collagen can suppress arthritis in ...

We have analyzed the DR-restricted presentation of the CII 256-276 peptide and identified two analog peptides that suppress arthritis in the context of DRB1*0401. These experiments represent the first description of an analog peptide of type II collagen recognized by T cells in the context of the human DR4 molecule that can suppress ...

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